Pixote, a 10-year-old runaway boy, is arrested on the streets of Sao Paulo during a police round-up homeless people. Pixote endures torture, degradation, and corruption at a local youth detention center where two of the runaways are murdered by policemen who frame Lilica, a 17-year-old trans hustler. Pixote helps Lilica and three other boys escape, and they survive by lives of crime that only escalate to more violence and death.